Summarized as follows: Abstract: The purpose of the prescription tablets on the CMST research and screening， and quality of research and quality Method of raw materials compatibility testing， orthogonal filter materials usage， HPLC determination of CMST content， the dissolution test by dissolution Results of water lactose F-100， HPC-SSL， CMC-Ca， magnesium stearate and CMST raw materials of these four good compatibility; materials suitable for the amount of: lactose monohydrate F-100 was 2%， HPC- SSL is 3%， CMC-Ca 3%， 8% magnesium stearate， and the remaining 80% of the main drug CMST; HPLC chromatographic conditions are used and method of CMST content measured was 2%， resolution 81， theoretical tower plate number 7205， tailing factor 14， are in reasonable range; made good CMST film dissolution， 30min dissolution of more than 90%， up to Conclusion lactose monohydrate F-100， HPC-SSL， CMC-Ca， magnesium stearate can be used for making these four materials CMST films， and obtained the optimum dosage; active chromatographic conditions HPLC method for determination of CMST content; with prescriptions obtained over the CMST technology dissolution good film to verify the correct selection of prescription; completed the development of quality standards of trial， is Questions added: Key words: CMST; prescription process; materials selection; HPLC method; dissolution test; quality
