Microorganisms in the field of modern biotechnology applications is very broad, microorganisms in many areas play an important role, is To let more people understand microbes and its role, the paper will be four areas on the Namely: microbes in the food industry in the application of micro-organisms and energy, micro-organisms, and new agriculture, medical microbiology in the One of the bacteria to produce methane, hydrogen and ethanol produced from bacteria to produce energy on behalf of the microorganisms to the main group classification, the metabolic energy generation and application of the mechanism of such microbes to produce energy at the same time a brief overview of the microbial New agriculture in a wide range of applications, such as the development of micro-organisms feed, microbial fertilizer, microbial pesticides, microbial food, energy and microbial agents, such as environmental microbiology, microbial analysis of the prospects for the development of new agricultural and discussed the development of micro-organisms in the important new drugs Done a role